On January 25, 2025, Health Canada (HC) announced a government notice regarding the use of trisiloxane (3-ethyl-1,1,1,3,5,5,5-heptamethyl-) in cosmetics in the Canada Gazette, Part I, Volume 159, Number 4. The notice states that trisiloxane is not listed on Canada’s Domestic Substance List. Therefore, due to potential concerns regarding reproductive, developmental, and oral toxicity, particular..